Laboratories' PhD project proposals (2009/10)

Date : 29/04/2009

Laboratory
Molecules Therapeutiques in silico (MTi)
Université Paris Diderot - Inserm U973
Batiment Lamarck, 5e etage
5 rue Marie-Andrée Lagroua Weill-Halle
75205 PARIS CEDEX 13
Director : Bruno VILLOUTREIX

PhD Supervisor
Maria Miteva
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 157278392

Subjects / Tools-Methodologies:
1 : drug design / in silico lead discovery and optimisation
2 : in silico screening / structure-based, ligand-based, docking
3 : structural bioinformatics / protein electrostatics, molecular dynamics

Website : www.mti.univ-paris-diderot.fr

Date : 20/04/2009

Laboratory
Laboratoire de RMN
ENS/UPMC/CNRS
Departement de Chimie
Ecole Normale Superieure
24, rue Lhomnd
75231 Paris Cedex 05
Director UMR 7203 - Solange Lavielle

PhD Supervisor
Daniel Abergel
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 44 32 33 44

Subjects / Tools-Methodologies:
1 : Prediction of Protein Dynamics / Computational (non-MD) Approaches
2 :Analysis of NMR Relaxation Data / Computational (non-MD) Approaches
3 : Protein Conformational Entropy / Computational (non-MD) Approaches

Date : 20/04/2009

Laboratory
Laboratoire de RMN
ENS/UPMC/CNRS
Departement de Chimie
Ecole Normale Superieure
24, rue Lhomnd
75231 Paris Cedex 05
Director UMR 7203 - Solange Lavielle

PhD Supervisor
Geoffrey Bodenhausen
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 44 32 33 89

Subjects / Tools-Methodologies:
1 : Experimental Protein Dynamics / Solid-State NMR Spectroscopy
2 :Theoretical Protein Dynamics / Computational (non-MD) Approaches
3 : Protein Crystallization / Typical Biochemical Techniques

Date : 25/03/2009 updated 18/04/2009

Laboratory
Research Center of the ICM
CNRS UMR7225 INSERM UMR975 UPMC
Hôpital de la Pitié Salpétrière
47 Bd de l'Hôpital 75013 Paris
Director : Dr B. Zalc

PhD Supervisor
Marie-Claude Potier
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 42 16 21 46

Subjects / Tools-Methodologies
1 : Neurobiology / molecular and cellular biology
2 : Microfluidics / photopolymerisation and digital microfluidics
3 : Alzheimer / histopathology

Date : 17/04/2009

Laboratory
Evolution of Nematode Development
Institut Jacques Monod,
UMR7592, CNRS-Université Paris-Diderot
402B 15 rue Hélène Brion
75205 Paris cedex 13
Director : Giuseppe Baldacci

PhD Supervisor
Marie-Anne Felix
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 57 27 80 67

Subjects / Tools-Methodologies:
1 : evolution / natural variation, evolutionary genetics
2 : ecology / sampling, life history
3 : pathogens, immunity/ C. elegans, microscopy, genetics, RNAi,

website: http://www.pasteur.fr/ip/easysite/go/03b-00001l-022/objectives

Date : 17/04/2009

Laboratory
Groupe Imagerie et Modélisation
Institut Pasteur
25 rue du Docteur Roux 75015 Paris
Director : Christophe Zimmer

PhD Supervisor
Christophe Zimmer
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 140613891

Subjects / Tools-Methodologies:
1 :nuclear organization / computational data analysis
2 : chromosomes / physical models
3 : epigenetics / super-resolution microscopy

website: http://www.pasteur.fr/ip/easysite/go/03b-00001l-022/objectives

Date : 07/04/2009

Laboratory
UMR 214 Ingénierie analytique pour la qualité des aliments
AgroParisTech
16 rue Claude Bernard
75005 Paris
Unit Director :Douglas RUTLEDGE

PhD Supervisor
Valérie Camel
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 144081725

Subjects / Tools-Methodologies:
1 :Persistent organic pollutants (POP) / Extraction and chromatographic analyses
2 :Biomarker analysis / Analysis of POP in biological samples
3 :Risk assessment / Modelling

Date : 03/04/2009

Laboratory
Modeling cellular Biology
Dept. Biology
46 rue d'Ulm
75005 Paris
Unit Director : Triller

PhD Supervisor
David Holcman
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 144323661

Subjects / Tools-Methodologies:
1 :cluster of telomeres / modeling and experiments
2 :motion of random objects / modeling and simulation
3 :applied mathematics / partial differential equations

Date : 02/04/2009

Laboratory
Equipe "Réseaux génétiques et morphodynamiques cellulaires"
CNRS-DEPSN UPR 2197
INAF bat 33
Avenue de la Terrasse
91198 Gif sur Yvette
Director : Philippe Vernier

PhD Supervisor
Nadine Peyriéras
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 69 82 41 42

Subjects / Tools-Methodologies:
1 : Embryology / Imagerie 4D
2 : Maths Appliques / Reconstruction phénoménologique
3 : BioPhysique / Reconstruction théorique

Date : 30/03/2009

Laboratory
PhysicoChimie Curie, Institut Curie
CNRS/ UMR 168
11 rue Pierre et Marie Curie
F - 75231 Paris Cedex 05
Director : Jean-François Joanny

PhD Supervisor
Patricia Bassereau
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 56 24 67 84

Subjects / Tools-Methodologies:
1 : Membrane curvature / optical tweezers
2 : protein-induced deformation / lipid nanotube
3 : cellular trafficking / micromanipulation

Date : 30/03/2009

Laboratory
Labo Ecology, Systematics and Evolution
UMR 8079 CNRS University Paris-Sud
bat 362
91405 Orsay Cedex
Director :Paul Leadley

PhD Supervisor
Anne-Caroline Prevot-Julliard
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 686787545

Subjects / Tools-Methodologies:
1 : population dynamics / Capture-Mark-Recapture
2 :conservation biology / Statistics and data analyses
3 :urban ecology / field studies, interdisciplinary projects

Date : 26/03/2009

Laboratory
Neurophysiology and New Microscopies Laboratory
CNRS UMR8154, INSERM S603
Université Paris Descartes
45, rue des Saints Pères
F - 75270 Paris Cedex 06
Director : Serge Charpak

PhD Supervisor
Valentina Emiliani
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 42 86 42 53

Subjects / Tools-Methodologies:
1 :Super resolution imaging / STED
2 : Wave front enginerring / Spatial light modulators
3 :Signal transmission in brain / Fluorescence

Date : 26/03/2009

Laboratory
RNA dynamics and Biomolecular Systems Lab
Institut Curie
CNRS-UMR168
11 rue Pierre et Marie Curie
75005 Paris
Director : Jean-François Joanny

PhD Supervisor
Hervé Issambert
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 56 24 64 74

Subjects / Tools-Methodologies:
1 : RNA self-assembly prediction / RNA structure modeling and bioinformatics
2 : RNA self-assembly in vitro / Atomique force microscopy
3 : RNA self-assembly in vivo/ in situ fluorescent microscopy

Date : 25/03/2009

Laboratory
Epigenomics Project
CNRS UPS3201
Tour Evry2, étage 10 523,
Terrasses de l'Agora
91034 EVRY Cedex
Director : Francois Kepes

PhD Supervisor
Alfonso Jaramillo
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 69 47 44 44

Subjects / Tools-Methodologies:
1 : mathematical modeling / software development
2 : computational design / software development
3 : bioimaging / microfluidics

Date : 25/03/2009

Laboratory
Laboratoire Analyse et Modelisation pour la Biologie et l'Environnement
UMR8587
Université d'Evry val d'Essonne
Blvd F.Mitterrand - Bat Maupertuis -
91025 EVRY
Director : J. Tortajada

PhD Supervisor
Marie-Pierre Gaigeot
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 69 47 01 41

Subjects / Tools-Methodologies
1 : charged nano-droplets / Molecular Dynamics simulations
2 : modeling evaporation of biomolecular edifices / Monte Carlo simulations
3 : mesoscopic models / develop mesoscopic interation models

Date : 25/03/2009

Laboratory
Physical chemistry of living systems (Physicochimie Curie)
Institut Curie, UMR168 CNRS/Institut Curie / Paris 6
F - 11, rue Pierre et Maris Curie 75231 Paris cedex 05
Director : Jean-François Joanny

PhD Supervisor
Julie Plastino
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 1 56 24 64 84

Subjects / Tools-Methodologies
1 : cytoskeleton / C. elegans
2 : cell motility / biophysics
3 : biomimetic systems / biochemistry

Date : 24/03/2009

Laboratory:
Neuroimagery & psychiatry
INSERM - CEA U797
97 Bd de Port Royal
75014 Paris
Director: Jean-Luc Martinot

Thesis supervisor
Jean-Luc MARTINOT
E-mail: This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
Phone: + 33 (0)1 58 41 28 41

Key subjects : Brain imaging, psychiatry, psychology

Keywords: MRI, psychometry, neuropsychology

Website : www.imagen-europe.com

Date : 23/03/2009

Laboratory
Laboratoire Matière et Systèmes Complexes
Université Paris 7 - CNRS
UMR 7057 Batiment Condorcet
10 rue Alice Domon et Léonie Duquet
F-75205 Paris Cedex 13
Director: Jean-Marc di Meglio

Thesis supervisor
Jean-François Berret
email: This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone: + 33 1 57 27 61 47

Subjects / Tools-Methodologies
1. Nanoscience / soft condensed matter
2. Biophysics / microscopy on single molecules
3. Physical chemistry / characterization of polymers and colloids

Date : 17/03/2009

Laboratory
Institut Jacques Monod (UMR 7592)
Membrane Traffic in Neuronal and Epithelial Morphogenesis
Universite Paris 7, Batiment Buffon, Labo 316B
4, rue Marie Andree Lagroua Weill-Halle
75013 Paris
Director : INSERM (U950) / Thierry Galli

PhD Supervisor
David TARESTE
email: This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : + 33 1 57 27 80 37

Subjects / Tools-Methodologies
1. In vitro reconstitution / Protein purification and labeling
2. Membrane protein dynamics / Confocal and PALM microscopy
3. Membrane fusion / FRET-based lipid mixing

Date : 20/03/2009

Laboratory :
EMBL, Heidelberg
Cell Biology and Biophysics
EMBL
Meyerhofstrasse 1
69117 Heidelberg
Germany
Director : Francois Nedelec

Thesis supervisor
François Nedelec
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
tél : + 49 622 138 785 97

Subjects / Tools & Methodologies
1. Cytoskeleton / Theory
2. Mitosis / Numerical simulation
3. Cell shape / Light microscopy

Eligible for INRA funding

Date : 16/3/2009

Thesis subject : "Développement d'une méthode de prédiction de novo de la structure 3D des protéines"

Laboratory 1
INRA
Département MIA-PHASE-MICA
Centre Jouy en Josas
Unité MIG 1077
Domaine de Vilvert
78 Jouy en Josas
Thesis supervisor 1 : Jean-François Gibrat, DR2 INRA, HDR

Laboratory 2
INRA
Département MIA
Centre Jouy en Josas
Unité MIA 341 MathCell
Domaine de Vilvert
78 Jouy en Josas
Thesis supervisor 2 :Antoine Vigneron, CR1 INRA

Before sending candidature, please contact supervisors :
Antoine Vigneron 01 34 65 22 19 This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
Jean-François Gibrat 01 34 65 28 97 This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

Profile and subjects :
Bioinformatique, Biophysique, Informatique

Eligible for INRA funding

Date : 16/03/2009

Thesis subject : "Meiotic recombination: from genetic determinants
to molecular and super-molecular mechanisms"

Laboratory 1
INRA
Département Génétique et amélioration des plantes.
Centre Gif sur Yvette
Unité UMR 8120 de génétique végétale
91190 Gif-sur-Yvette
Thesis supervisor 1 : Olivier Martin, HDR (Genetique Quantitative Fondamentale)

Laboratory 2
INRA
Département Génétique et amélioration des plantes.
Centre Versailles
Unité UR 2454
Route de Saint Cyr
78026 Versailles
Thesis supervisor 2 :Raphaël Mercier (Méiose et recombinaison).

Before sending candidature, please contact supervisors :
Olivier Martin 01 69 33 23 36 This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
Raphaël Mercier 01 30 83 39 89 This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

Profile and subjects
Masters Modélisation, Génétique
Génétique, Biologie intégrative

Subject eligible for INRA funding

Date : 16/03/2009

Thesis subject : "Role of tissue mechanics in plant morphogenesis"

Laboratory 1
INRA - BV
Centre Versailles
Unité UR501, Biologie cellulaire
Route de Saint Cyr 78026 Versailles, cedex
Thesis supervisor 1 :Alexis Peaucelle, Herman Höfte (Parois primaire)

Laboratory 2
Université Paris VII
Laboratoire Matière et Systèmes Complexes (MSC)
Unité UMR 7057
Bat. Condorcet case 7056.
10, Rue Alice Domont et Léonie Duquet
75205 Paris cedex 13
Thesis supervisor 2 : Atef Asinasios, HDR

Before sending candidature, please contact supervisor :
Alexis Peaucelle, 01 30 83 33 49, This e-mail address is being protected from spam bots, you need JavaScript enabled to view it

Profile and subjects :
Masters biologie moélculaire et physiologie végétale, physique avec intéreêt pour la biologie.
Biologie du développement, Physique : rhéologie

Date : 18/02/2009

Laboratory
LMGP-MINATEC
CNRS UMR5628
3 parvis Louis Néel
38016 GRENOBLE
Director : Bernard CHENEVIER

PhD Supervisor
Catherine PICART (Professor at Grenoble INP and Junior Member of the "Institut Universitaire de France for 2007-2012)
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : +33 4 56 52 93 11

Subjects / Tools-Methodologies:

1 : thin film mechanical properties / AFM nano-indentations
2 : cell differentiation / specific protein markers
3 : growth factor / quantification of protein expression

Date : 7/01/09

Laboratory
IMNC (Imaging and Modeling for Neurobiology and Oncology)
Paris 7/Paris 11 Universities/CNRS; UMR 8165
IMNC Laboratory
15 rue Georges Clémenceau
Bat 104
91406 Orsay Cedex
France
Director : Yves Charon

PhD Supervisor
Basile Grammaticos
This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
co-supervisor : Mathilde Badoual
email : This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
phone : + 33 1 69 15 72 01

Subjects / Tools-Methodologies
1. Modeling migrating cancerous cell that / numerical simulations, cellular automata
2. Statistical analysis of histological slices from h / image processing, statistical analysis
3. Related problems of statistical physics / mean field approximation, EDP...